The cultivation and migration in vitro of olfactory ensheathing cells from human olfactory mucosa.
- Author:
Qiubei ZHU
;
Huanhai LIU
;
Juntian LANG
;
Hu PENG
;
Shuwei ZHAO
- Publication Type:Journal Article
- MeSH:
Animals;
Cell Culture Techniques;
Cell Movement;
Cells, Cultured;
Humans;
Olfactory Mucosa;
cytology;
Rats
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(5):410-415
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the bionomics of the olfactory ensheathing cells (OECs) of human olfactory mucosa.
METHOD:To separate and cultivate the OECs of human and rat olfactory mucosa. To observe the cell growth, cell grouping and cell migration in vitro of the two types of OECs.
RESULT:Successfully separated and cultivated the OECs of human and rat olfactory mucosa. OECs of the human and rat olfactory mucosa had the similar cell growth, cell grouping and cell migration ability in vitro.
CONCLUSION:OECs of the human and rat olfactory mucosa have the similar bionomics in vitro, as a result, OECs of the human olfactory mucosa could be a reliable source of cell transplant for nerve injury.