Detection and grading of endolymphatic hydrops in Ménière's disease using 3D FLAIR MRI.
- Author:
Jin YAN
;
Liyan PENG
;
Hongzheng CHENG
;
Yonghua CUI
;
Aiguo LIU
- Publication Type:Journal Article
- MeSH:
Cochlea;
Contrast Media;
Ear, Inner;
Ear, Middle;
Gadolinium DTPA;
Humans;
Imaging, Three-Dimensional;
Injections;
Magnetic Resonance Imaging;
Meniere Disease;
diagnosis;
Vestibule, Labyrinth
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(5):421-424
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the extent of endolymphatic hydrops as shown by three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D FLAIR MRI) performed 24 hours after bilateral intratympanic gadolinium administration and discuss the positive rate of endolymphatic hydrops in vestibule and cochlea.
METHOD:Twenty-four hours after bilateral intra-tympanic 8 times diluted gadolinium administration, three-dimensional fluid-attenuated inversion recovery MRI, using a three-Tesla unit, was performed in 48 patients, and then assessed the extent of endolymphatic hydrops in the MRI images.
RESULT:Forty-eight patients showed different levels of enhancement of perilymth in the inner ear. In these patients, obvious signs of endolymphatic hydrops were visualized in vestibule,including 8 slight hydrops, 17 mild hydrops and 23 severe hydrops with a diagnostic rate of 83.3%. There were almost no complications in all 48 patients after bilateral intra-tympanic injection except short vertigo in some of them.
CONCLUSION:3D FLAIR MRI resonance imaging has a high positive diagnostic rate in assessing endolymphatic hydrops of Ménière's disease and provides direct imaging evidence for diagnosing Ménière's disease.
