Inhibit affection of resveratrol on the growth of Hep-2 cell line.
- Author:
Yunchuan LI
1
;
Yanwei XU
;
Dan HUANG
;
Linlin JIANG
;
Kesen LI
Author Information
1. Department of Otolaryngoloy-Head and Neck Surgery, Capital Medical University, Beijing, 100730, China. 1964liyunchuan@163.com
- Publication Type:Journal Article
- MeSH:
Cell Cycle;
drug effects;
Cell Line, Tumor;
Cell Proliferation;
drug effects;
Dose-Response Relationship, Drug;
Humans;
Resveratrol;
Stilbenes;
pharmacology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2007;21(24):1129-1131
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the inhibitory effect of resveratrol on growth of human laryngeal cancer cell line, Hep-2.
METHOD:Count cell number under microscope, MTT assay was used to determine the cell growth inhibitory rate. Soft agar colony forming experiment was performed to observe the proliferation ability, before or after resveratrol treatment.
RESULT:Resveratrol was able to depress cell growth and inhibit cell proliferation.
CONCLUSION:Resveratrol strongly inhibit Hep-2 cell proliferation in a time- and dose-dependent manner.
