Biocompatibility study of polylactic/glycolic acid and Schwann cell.
- Author:
Huaidong DU
1
;
Hongbin TIAN
;
Liang ZHOU
;
Jie TIAN
Author Information
1. Department of Otorhinolaryngology, Affiliated Eye Ear Nose Throat Hospital of Fudan University, Shanghai, 200031, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Biocompatible Materials;
Cells, Cultured;
Lactic Acid;
Nerve Regeneration;
Polyesters;
Polyglycolic Acid;
Polymers;
Rats;
Rats, Sprague-Dawley;
Schwann Cells;
cytology;
immunology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2008;22(5):226-228
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To examine the biocompatibility of polylactic/glycolic acid (PLGA) and Schwann cells.
METHOD:Schwann cells were harvested from rat brachial and sciatic nerves. Schwann cells were cultured with PLGA, observed by phase-contrast microscopy and electron microscopy.
RESULT:Schwann cells could attach and proliferate on the surface of the PLGA.
CONCLUSION:The PLGA has good cellular biocompatibility. It can be used as biomaterial for tissue engineering.
