The experimental research for electrophysiology detection and electron microscopic observation on the ultrasonically activated shears injures recurrent laryngeal nerve at different time.
- Author:
Zheng ZHOU
1
;
Jiadong WANG
;
Xin LI
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Renji Hospital, Shanghai Jiaotong University, Shanghai 200001, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Disease Models, Animal;
Electrophysiological Phenomena;
Rabbits;
Recurrent Laryngeal Nerve Injuries;
Surgical Instruments;
adverse effects;
Ultrasonic Therapy;
adverse effects;
instrumentation
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2010;24(21):990-992
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the correlative factors on recurrent laryngeal nerve (RLN) injuries caused by ultrasonically activated shears (UAS).
METHOD:Fifteen New Zealand rabbits (thirty recurrent laryngeal nerves) were randomly divided into 5 groups: group 1 and group 2 are those UAS works 1 mm away from RLN for 2 s and 4s separately, group 3 and group 4 are those UAS works 3 mm away from RLN for 2 s and 4 s separately, and the other one is control group. Electrophysiology was detected in each group. The RLN injuries of group 2, 3 and control group were observed with electron microscope.
RESULT:Significant differences on amplitude and latency were found in all the experimental groups except group 3 when compared to the control group, and between every two experimental groups as well. Histological changes such as obviously swelling myelin lamellar, loosen and disordered structures, bubble-liked axon collapse and liquefaction of axoplasm were only observed in group 2.
CONCLUSION:UAS is a new apparatus for cutting and coagulating in operations, which is safe and reliable to be applied for endoscopic surgery. It will be a new choice for treating thyroid neoplasm.
