Evaluation of influencing factors and different repair mechanism of tympanic membrane perforations.
- Author:
Zhengcai LOU
1
;
Yunxing HU
;
Yanhui ZHANG
;
Huaying CHEN
;
Jian YANG
Author Information
1. Department of Otolaryngology, the Central Hospital of Yiwu, Yiwu, 322000, China. louzhengcai@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Adult;
Female;
Humans;
Middle Aged;
Tympanic Membrane Perforation;
etiology;
therapy;
Wound Healing;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2011;25(1):20-22
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:Evaluation of different repair mechanism and influencing factors for Prognosis of tympanic membrane perforations.
METHOD:One hundred and twelve female patients of tympanic membrane perforations were randomly divided into two groups: control group (natural repair group) and treatment group (gelatin sponge patch bonded repair group). The perforation healing were dynamically observed in two groups by endoscope.
RESULT:The result show that low, medium and high perforations healing rates were 100.00%, 90.48%, 93.33%. The healing time of low, medium and high was (9.0 +/- 2.8) d, (13.0 +/- 2.6) d, (22.0 +/- 4.7) d, the epithelial layer reverse growth in 5 cases. The result show that low, medium and high perforations healing rates were 91.67%, 95.24%, 84.62%. The healing time of low, medium and high was (11.0 +/- 3.7) d, (24.0 +/- 3.8) d, (36.0 +/- 2.1) d, 2 cases were undergone surgeries.
CONCLUSION:There are differences in repair mechanism between natural repair and patch bonded repair patch bonded repair can promote granulation hyperplasia, it can help recovering and lessening the patient's conductive hearing loss and occasional tinnitus. granulation hyperplasia and the healing time is closely related. The epithelial layer reverse growth may affect the healing of tympanic membrane perforation.
