Surgery added with fluconazole in treatment of fungal rhinosinusitis.
- Author:
Zhiyuan ZHANG
1
;
Jian ZHANG
;
Wugen LUO
;
Hongqun JIANG
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Nanchang University, Nanchang, 330006, China. zhangjian115123@hotmail.com
- Publication Type:Journal Article
- MeSH:
Adult;
Antifungal Agents;
therapeutic use;
Female;
Fluconazole;
therapeutic use;
Humans;
Male;
Sinusitis;
drug therapy;
microbiology;
surgery;
Treatment Outcome
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2012;26(15):692-696
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the effect of surgery added with antifungal agents in treatment of fungal rhinosinusitis.
METHOD:One hundred and two consecutive patients with fungal rhinosinusitis were randomly divided into two groups: the control group (n=48) were treated with surgery alone, the treatment group (n=54) were treated with surgery plus antifungal therapy during operation and postoperation. The patients were followed up for 6 months and the relapse rates between two groups were compared.
RESULT:No relapse was observed in the treatment group. The relapse rate of the control group was 20.8% (P < 0.01).
CONCLUSION:Surgery plus antifungal therapy can prevent the relapse of fungal rhinosinusitis significantly.
