Serum allergen-specific IgE in patients with eosinophilic nasal polyps.
- Author:
Ming XU
1
;
Feng ZHAO
;
Anmin SHEN
;
Haojie ZHOU
Author Information
1. Department of Otorhinolaryngology, the Affiliated Hospital, Medical School of Ningbo University, Ningbo, 315020, China. entxm@hotmail.com
- Publication Type:Journal Article
- MeSH:
Adult;
Allergens;
immunology;
Animals;
Eosinophils;
cytology;
Female;
Humans;
Immunoglobulin E;
blood;
Leukocyte Count;
Male;
Middle Aged;
Nasal Polyps;
blood;
immunology;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2012;26(17):772-773
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the relationship between airborne allergen and patients with nasal polyps (NP).
METHOD:Eighty-three cases of patients with NP were classified into the eosinophilic group(ENP) and non eosinophilic group (nENP) in terms of the EOS count in NP specimen, all patients underwent specific-IgE test with standardized allergens and the results were analyzed.
RESULT:The specific-IgE positive rate was 59.26% in ENP group and 23.21% in the nENP group respectively (P < 0.01), and the positive rate of ENP was statistical significance compared with nENP. The dust mite was the most prevalent airborne allergen in ENP group.
CONCLUSION:The perennial airborne allergens may play a certain role in the etiology and pathogenesis of NP.
