Genetic study of allergic diseases.
- Author:
Yuan ZHANG
1
;
Luo ZHANG
Author Information
1. dr.luozhang@gmail.com
- Publication Type:Journal Article
- MeSH:
Asthma;
genetics;
Gene-Environment Interaction;
Humans;
Hypersensitivity;
genetics;
Immunoglobulin E;
Rhinitis, Allergic, Perennial;
genetics;
Rhinitis, Allergic, Seasonal;
genetics;
Risk Factors
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2012;26(17):809-813
- CountryChina
- Language:Chinese
-
Abstract:
Allergic diseases mentioned in this review is regarding to I type allergic inflammation induced by an IgE-mediated reaction, including asthma, allergic rhinitis, atopic dermatitis and food allergy. It is convinced that allergic diseases belong to multiple genes diseases and are controlled by both genetic and environmental factors. Meanwhile there exists gene-gene as well as gene-environment interactions during the development of the disease. The aim of this review is to summarize the toolkit, advance, inherent difficulties and future clinical application prospect in genetic studies of allergic disease.