Serological detection of specific IgE in allergic rhinitis.
- Author:
Yuemei KAI
1
Author Information
1. Department of Otolaryngology, Peking University Shenzhen Hospital, Shenzhen, 518036, China. Kaiym@126.com
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Allergens;
blood;
Animals;
Antigens, Dermatophagoides;
immunology;
Child;
Child, Preschool;
Female;
Humans;
Immunoglobulin E;
blood;
Male;
Middle Aged;
Pyroglyphidae;
Retrospective Studies;
Rhinitis, Allergic;
Rhinitis, Allergic, Perennial;
blood;
epidemiology;
Seroepidemiologic Studies
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2012;26(20):933-935
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the positive rate of allergen-specific serum IgE in local patients with allergic rhinitis, and compare the positive rate of allergen-specific serum IgE across different age groups and between sexes.
METHOD:Inhalant and ingested serum allergen-specific IgE was detected in 145 patients with allergic rhinitis. Patients were grouped by age and sex, and then the positive rate was compared between the two groups.
RESULT:Ninety-four out of 145 cases had positive allergen specific IgE, and the positive rate was 64.8%. There were 45 cases with single positive allergen, accounting for 47.9%. And there were 49 cases with two or multiple positive allergens, mainly inhalant allergens, accounting for 52.1%. The difference of allergen-specific IgE positive rate between men and women was not statistically significant (P>0.05); but the positive rate between adults and adolescents was statistically significant (P<0.05).
CONCLUSION:Inhalant allergen is a major cause of allergic rhinitis in local people. The positive rate of household dust mites and dermatophagoides was highest (87.4%). The positive rate of specific IgE was associated with age, and adolescents have higher positive rate than adults.
