Progress in application of mesenchymal stem cells for nasal inflammation disease.
- Author:
Zhibang HU
;
Xia GAO
- Publication Type:Journal Article
- MeSH:
Adult Stem Cells;
transplantation;
Autoimmune Diseases;
Cell Differentiation;
Humans;
Inflammation;
therapy;
Mesenchymal Stem Cell Transplantation;
Mesoderm;
cytology;
Nose Diseases;
therapy;
Wound Healing
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(9):859-862
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells (MSCs) are adult stem cells which derived from the embryonic mesoderm. They have a high proliferative ability and can differentiate into various tissues of mesodermal origin including bone, cartilage and adipose tissue in vitro. Moreover, MSCs have also been shown to produce anti-inflammatory molecules which can modulate cellular and humoral immune responses. Because of their easy preparation, the capacity for self-renewal, multi-lineage differentiation and immunoregulatory effect, MSCs therapy becomes a promising tool in the treatment of tissue regeneration, anti-inflammation, and autoimmune diseases. In this review we will focus on the application of MSCs for nasal inflammation disease.
