Lymphoepithelial carcinoma in salivary glands: clinical and pathological analysis of 17 cases.
- Author:
Xuemin YIN
;
Guoxiang XU
;
Leitao ZHANG
;
Zhifeng CHEN
;
Xiao LIU
;
Junwei ZHANG
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Female;
Humans;
Male;
Middle Aged;
Neoplasm Recurrence, Local;
Neoplasms, Squamous Cell;
pathology;
secondary;
Parotid Neoplasms;
pathology;
Rare Diseases;
pathology;
Retrospective Studies;
Salivary Gland Neoplasms;
pathology;
Salivary Glands;
pathology;
Submandibular Gland Neoplasms;
pathology;
Treatment Outcome
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(21):1171-1174
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:Lymphoepithelial carcinoma (LEC) of salivary glands is a rare malignant neoplasm. The purpose of this research was to investigate the clinicalpathologic features and treatment methods of this rare disease.
METHOD:The clinical data and treatment outcomes of 17 patients from 2006 to 2012 were reviewed retrospectively.
RESULT:Ten males and seven females with a ratio of 1. 43:1 were involved. The II, III, IV stage cases were 7 (41.2%), 4 (23.5%), 6 (35.3%), respectively. The average follow-up duration was 2.56 years, and 12 patients had no evidence of recurrence. Five patients had local recurrence and (or) distant metastases within three years after surgery, including 4 deaths.
CONCLUSION:LEC in salivary gland is a high grade malignant tumor in oral and maxillofacial region, occurring predominately in parotid gland and submandibular gland. To prevent distant metastasis, radical surgery combined with chemoradiotherapy should be adopted.
