One case of throat B-cell lymphoma with ipsilateral thyroid papillary carcinoma.
- Author:
Zhenying CUI
;
Bo ZHOU
;
Zehai DENG
- Publication Type:Case Reports
- MeSH:
Carcinoma;
pathology;
Carcinoma, Papillary;
pathology;
Female;
Hashimoto Disease;
pathology;
Humans;
Immunohistochemistry;
Lymphoma, B-Cell, Marginal Zone;
genetics;
pathology;
Middle Aged;
Neck;
Neoplasms, Multiple Primary;
pathology;
Pharyngeal Neoplasms;
pathology;
Pharynx;
Thyroid Cancer, Papillary;
Thyroid Neoplasms;
pathology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(21):1220-1221
- CountryChina
- Language:Chinese
-
Abstract:
UNLABELLED:A female patient of 56 years old had hoarseness that seems worse after talking excessively,which occasionally associated with slightly sore throat and pharyngeal foreign body sensation. The symptoms are not associated with sore throat, fever, night sweats, not drinking cough, breathing and swallowing difficulties, but no cough, bloody sputum. Neck ultrasound can be showed: goiter and real echo uneven thickening, increased blood supply pan; the right thyroid lobe multiple cysts pan. Enhanced CT shows occupying lesions were found out in the right side of the supraglottic larynx gap and the right lobe of the thyroid, nature to be determined. Full thyroid function showed: thyroid microsomal antibodies 278.2 u/ml, the rest of the indicators in the normal range. Other routine preoperative examinations were normal. Immunohistochemistry: CD45(++) CD68(+) CD99(++) EMA(-) CK(-) Sclc(-) TTF-1(--) CgA(-) SY(-) NSE(--) S-100(-) ESA(-). Supported by immunohistochemistry, hyperplasia organizations was diffuse lymphoid tissue. Through expert consultation by superior hospital the pathology showed: Hashimoto's thyroiditis with thyroid papillary carcinoma (lesions of the right thyroid); Lesion on the right side of the throat gene rearrangement results show: B lymphocyte clonal consider mucosa-associated extranodal marginal zone B-cell lymphoma the gene rearrangement that the right side of the throat disease is: B lymphocyte clonal, be considerd mucosa-associated extranodal marginal zone B-cell lymphoma.
DIAGNOSIS:throat B-cell lymphoma; thyroid papillary carcinoma (right side); Hashimoto's thyroiditis (right side).
