One case of hereditary angioneurotic laryngeal edema.
- Author:
Wei HUANG
;
Heying YUE
;
Hua HU
- Publication Type:Journal Article
- MeSH:
Angioedemas, Hereditary;
diagnosis;
Complement C1 Inactivator Proteins;
analysis;
metabolism;
Complement C1 Inhibitor Protein;
Humans;
Laryngeal Edema;
diagnosis;
Recurrence
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(21):1222-1222
- CountryChina
- Language:Chinese
-
Abstract:
Hereditary angioneurotic laryngeal edema (HALE) is an autosomal dominant hereditary disease in which there is a decrease or defect in the C1 inhibitor (C1-INH). The pathophysiology of HALE is characterized by recurrent spontaneous episodes of transient edema of the laryngeal mucose and submucosal tissue with remission at irregular. Patients may die because of a life-threatening acute upper airway obstruction caused by laryngeal edema. HALE was diagnosed on the clinical symptoms, family history, and markedly decreased serum C1-INH activity and C1-INH protein.
