The clinical significance of 1,3-beta-D glucanase detection in plasma to the diagnosis of fungal rhinosinusitis.
- Author:
Jing YANG
1
;
Zhigang BIAN
;
Bo YU
;
Xin HU
;
Haibo ZHANG
;
Zhiwei CAO
Author Information
1. Department of Otolaryngology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Case-Control Studies;
Endo-1,3(4)-beta-Glucanase;
blood;
Female;
Fungi;
Humans;
Male;
Middle Aged;
Mycoses;
blood;
diagnosis;
Sinusitis;
blood;
diagnosis;
microbiology;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(11):565-566
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the clinical significance of 1,3-beta-D glucanase detection in plasma to the diagnosis of fungal rhinosinusitis.
METHOD:MB-80 rapid microorganism detection system was used to detect preoperative and postoperative 1,3-beta-D glucanase in plasma of 37 patients of fungal rhinosinusitis which were treated by endoscopic sinus surgery and confirmed by postoperative pathology. Blood samples of 47 patients who underwent endoscopic surgery(fungal rhinosinusitis excluded) were taken as control group.
RESULT:1,3-beta-D glucanase content is more than 10 pg/ml in 34 cases of the fungal rhinosinusitis group,and every 1,3-beta-D glucanase content of 47 control cases is less than 10 pg/ml. Significant difference is found between case and control groups(chi2 = 72.6, P < 0.01).
CONCLUSION:1,3-beta-D glucanase detection in plasma is a simple,rapid diagnostic method of fungal rhinosinusitis.
