Meta analysis of the relationship between human papilloma virus and nasal inverted papilloma.
- Author:
Wu XIAO
1
;
Shanfeng LIU
;
Liyin WANG
;
Huimin LI
;
Wenwei WU
;
Zhenhai WANG
Author Information
1. Department of Otolaryngology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
- Publication Type:Journal Article
- MeSH:
DNA, Viral;
Humans;
Nose Neoplasms;
virology;
Papilloma, Inverted;
virology;
Papillomaviridae;
Papillomavirus Infections;
pathology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2013;27(11):572-576
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the relationship between human papilloma virus (HPV) infection and the occurrence, recurrence and malignant transformation of nasal inverted papilloma (NIP).
METHOD:With comprehensive retrieval of related literature that had been published in databases included Pubmed (1990--2011), Cochrane Library, CNKI (1979-2011), VIP (1989-2011), CBM (1990-2011) and WANFANG Meta-analysis software Rev-Man 5.0 was used to analyze the raw data and to calculate the value of combined odd ratio (OR) and 95% confidence interval (CI).
RESULT:According to Meta-analysis, the occurrence group between HPV and NIP, the OR was 34.44 and 95% CI was 12.96-91.56; the recurrence group, the OR was 3.66 and 95% CI was 1.77-7.56, to the high-risk HPV, the OR was 1.94 and 95% CI was 0.30-12.58; the malignant transformation group, the OR was 1.79 and 95% CI was 0.94-3.40 to the high-risk HPV, the OR was 49.35 and 95% (CI was 0.45-11.23.
CONCLUSION:HPV may play an important role in the occurrence and recurrence of NIP and high-risk HPV was closely related to the progress of NIP.
