The Survival of Freely Grafted Orbital Fat on Porous Polyethylene Orbital Implants in the Rabbit.
10.3341/kjo.2006.20.3.143
- Author:
Nam Ju KIM
1
;
Ho Kyung CHOUNG
;
Sang In KHWARG
Author Information
1. Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. khwarg@.snu.ac.kr
- Publication Type:Original Article ; Comparative Study ; Research Support, Non-U.S. Gov't
- Keywords:
Exposure;
Medpor(R);
Orbital fat
- MeSH:
Time Factors;
Rabbits;
Porosity;
*Polyethylene;
*Orbital Implants;
*Graft Survival;
Follow-Up Studies;
*Biocompatible Materials;
Animals;
Adipose Tissue/cytology/*transplantation
- From:Korean Journal of Ophthalmology
2006;20(3):143-146
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To investigate the long term survival of orbital fat grafted on a Medpor(R) implant as a method of preventing porous polyethylene orbital implant (Medpor(R)) exposure in anophthalmic sockets. METHODS: In one orbit in each of 8 rabbits, a small amount of retrobulbar orbital fat was grafted between the anterior surface of the Medpor(R) implant and overlying conjunctiva, during the enucleation and Medpor(R) implantation procedure. Two rabbits were sacrificed at 2, 4, 8 and 12 weeks postoperatively and grafted orbital fats were examined by light microscopy. RESULTS: Grafted orbital fat was well-maintained at 2 and 4 weeks, postoperatively. However, fat amounts were significantly reduced at 8 weeks, and viable fat was barely visible at 12 weeks. CONCLUSIONS: In rabbits, orbital fat grafted on Medpor(R) implants was gradually resorbed, and the fat-occupied volume was not maintained.
