Short-term efficacy and factors of specific immunotherapy on patients with allergic rhinitis.
- Author:
Congli GENG
;
Xiaopei YUAN
;
Zhimin XING
;
Lisheng YU
;
Min WANG
;
Yuqiang LIN
;
Yan LIU
;
Gai ZHANG
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Immunoglobulin E;
blood;
Immunotherapy;
Pyroglyphidae;
Rhinitis, Allergic;
therapy;
Skin Tests
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(21):1857-1863
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the short-term efficacy and investigate the factors of specific immunotherapy (SIT) efficacy of allergic rhinitis.
METHOD:Fifty-seven patients with allergic rhinitis to dermatophagoides pteronysinus were included to receive SIT. Pair t-test was used to compare the symptom scores, visual analogue scores (VAS) and medication scores in patients before SIT and into maintain treatment statement to evaluate the clinical efficacy. T-test and Spearman correlation analysis were used to analyze the correlation between gender, age,reaction condition of skin prick test (SPT) and serum sIgE and the efficacy of SIT.
RESULT:SIT was able to significantly reduce the symptom scores, VAS and medication scores. But the correlation between gender, age, SPT, and sIgE and theefficacy of SIT were not significant.
CONCLUSION:SIT is effective in the short-term treatment of AR. Further research is needed to investigate the factors that impact the efficacy of SIT.
