Efficacy of intratympanic steroid injection as supplementary or initial treatment for sudden sensorineural hearing loss.
- Author:
Jingcai CHEN
;
Jun YANG
;
Huan JIA
;
Jun SHI
;
Yun LI
;
Hao WU
- Publication Type:Journal Article
- MeSH:
Hearing Loss, Sensorineural;
drug therapy;
Hearing Loss, Sudden;
drug therapy;
Humans;
Injection, Intratympanic;
Steroids;
administration & dosage;
therapeutic use;
Treatment Outcome;
Tympanic Membrane
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(19):1691-1694
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the efficacy of intratympanic steroid injection as supplementary or initial treatment for sudden sensorineural hearing loss (SSNHL).
METHOD:A total of 68 patients diagnosed with SSNHL were randomized into group A (45 cases including systemic steroid for 33 cases and systemic steroid + intratympanic steroid as supplementary treatment for 12 cases) and group B (23 cases, initial intratympanic steroid). Then observe the therapeutic effect in two groups.
RESULT:The total effective rate was 55.6% in group A and 56.5% in group B. No statistical difference was detected between these two groups (P > 0.05). There was statistical difference after therapy of intratympanic steroid as supplementary treatment for 12 patients due to poor hearing improvement after systemic steroid in group A (P < 0.05).
CONCLUSION:Both systemic and intratympanic steroid injection for SSNHL are effective. The efficiency of intratympanic steroid injection as supplementary or initial treatment for SSNHL is similar to that of systemic steroid. The intratympanic steroid injection for SSNHL as initial protocol or as supplementary treatment when poor hearing improvement after systemic steroid is recommended.
