The changes and significance of IL-6 levels in patients with OSAHS associated Type 2 diabetes Mellites.
- Author:
Peilin HUI
;
Shuangbao JIA
;
Wei MA
;
Lijun ZHAO
;
Jinfeng WANG
;
Xiaoquan WEI
;
Liya ZHOU
;
Manke DAI
;
Wenjuan ZHANG
;
Yuping XIE
- Publication Type:Journal Article
- MeSH:
Case-Control Studies;
Diabetes Mellitus, Type 2;
blood;
complications;
Humans;
Interleukin-6;
blood;
Sleep Apnea, Obstructive;
blood;
complications
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(19):1726-1728
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the changes of serum interleukin-6 (IL-6) level in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and OSAHS associated type 2 diabetes mellitus (T2DM) and their significance.
METHOD:All observed subjects were divided into 3 groups: 20 cases of normal subjects, 35 cases of simple OSAHS patients, 48 cases of OSAHS associated T2DM patients, IL-6 concentrations of serum were measured by the enzyme-linked immunosorbent.
RESULT:IL-6 level was higher in the group of OSAHS with T2DM than the group of OSAHS and the healthy control group (P < 0.05); IL-6 level was higher in the simple OSAHS group than the healthy controls.
CONCLUSION:IL-6 and other inflammatory factors may involved pathological physiological process in OSAHS patients sugar metabolic abnormalities; and is associated with the development of OSAHS associated with type 2 diabetes.
