Nasal endoscope negative pressure cleaning and sinupret drops to treat radiation nasosinusitis.
- Author:
Wenbiao LIN
;
Chaokun QUAN
;
Longcheng ZHANG
- Publication Type:Journal Article
- MeSH:
Carcinoma;
Endoscopy;
Humans;
Incidence;
Nasal Cavity;
Nasal Lavage;
Nasopharyngeal Carcinoma;
Nasopharyngeal Neoplasms;
radiotherapy;
Plant Extracts;
administration & dosage;
therapeutic use;
Radiotherapy;
adverse effects;
Sinusitis;
therapy;
Sodium Chloride
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2015;29(23):2019-2022
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the effect of nasal endoscope negative pressure cleaning and sinupret drops to treat radiation nasosinusitis (RNS).
METHOD:One hundred and fifty-three patients with nasopharyngeal carcinoma were randomly divided into treatment group A, B, C . Group A using nasal endoscope negative pressure cleaning and sinupret drops, group B using nasal endoscope negative pressure cleaning and normal saline spray washing, group C using saline nasal irrigation through nasal catheter. All patients with sinusitis condition were evaluated at the end of radiotherapy, three months and six months after radiotherapy.
RESULT:Comparison between groups, three periods of RNS incidence, moderate to severe RNS incidence are A < B < C. Six months after radiotherapy, group A compared with group C, there are significant difference (P < 0.01), group A and group C compared with group B respectively, the difference was statistically significant (P < 0.05).
CONCLUSION:Nasal endoscope negative pressure cleaning and sinupret drops can significantly reduce the long-term incidence of RNS, especially obviously reduce the incidence of moderate to severe RNS,which is a practical and effective method to treat RNS.
