Clinical analysis of primary laryngeal amyloidosis.
- Author:
Chaoping HUANG
1
;
Siquan TANG
;
Jianhui ZHANG
;
Yanli HUANG
;
Qingchun PAN
;
Rui ZHAO
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China.
- Publication Type:Journal Article
- MeSH:
Age Factors;
Amyloidosis;
pathology;
surgery;
Biopsy;
Humans;
Immunoglobulin Light-chain Amyloidosis;
Laryngeal Diseases;
pathology;
surgery;
Laryngoscopy;
Larynx;
pathology;
Retrospective Studies;
Vocal Cords;
pathology
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2012;26(9):389-391
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the clinical features and treatment protocols of primary laryngeal amyloidosis.
METHOD:Retrospective study of 5 patient hospitalized from 1996 - 2011. All of the patients by resection lesions, including four routine throat tumor resection, and burst throat by supporting laryngoscope in 1 case, all did not give lesions resection radiation and hormone therapy.
RESULT:All the 5 patients recovered clinically. There were 3 patients followed up for 0.3-7.5 years with a mean time of 3.3 years without recurrence, 2 patients lost follow-up.
CONCLUSION:Middle ages seemed to be more vulnerable. The most common disease region is true vocal cord, followed by false vocal cord, epiglottis former clearance etc. Early surgical treatment of this disease is the most important treatment, larynx endoscopic and CT for the diagnosis of great value, and pathologic biopsy especially Congo red stain positive is the basis of the specific diagnosis of this disease.
