The study on AHI, LSaO2 and ET-1 in patients with obstructive sleep apnea-hypopnea syndrome after H-UPPP.
- Author:
Xiaosong WU
1
;
Yi YU
;
Dongli HU
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, Yongchuan Hospital, Chongqing Medical University, Chongqing, 402160, China. wxsent2000@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Adult;
Apnea;
blood;
surgery;
Disorders of Excessive Somnolence;
blood;
surgery;
Endothelin-1;
blood;
Female;
Humans;
Male;
Middle Aged;
Palate, Soft;
surgery;
Pharynx;
surgery;
Polysomnography;
Sleep Apnea, Obstructive;
blood;
surgery;
Sleep Stages;
Snoring;
blood;
surgery;
Uvula;
surgery
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2012;26(12):539-541
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the treatment effect of H-UPPP on patients with obstructive sleep apnea hypopnea syndrome (OSAHS).
METHOD:Seventy-nine patients were enrolled in our study. Among which 49 patients were done with H-UPPP, and the other 30 patients were done with UPPP. AHI and LSaO2 were monitored by polysomnography and plasma endothelins-1 were tested with enzyme linked immunosorbent assay (ELISA) before and after operation.
RESULT:Forty-one patients were improved with reduced snoring and daytime sleepiness one year after operation in H-UPPP group,and the overall efficiency was 83.7%. Twenty-six patients were improved with reduced snoring and daytime sleepiness one year after operation in UPPP group, and the overall efficiency was 86.7%. There were significant differences of AHI, LSaO2 and ET-1 before and after operation between the two groups. Negative correlation was showed between AHI and LSaO2, also between LSaO2 and ET-1.
CONCLUSION:Both H-UPPP and UPPP were proved to be effective to patients with OSAHS. The perioperative complications with H-UPPP was less than UPPP.
