Clinical analysis of laryngeal neuroendocrine carcinoma.
- Author:
Cai LI
1
;
Liang ZHOU
;
Yan SHEN
;
Li ZHU
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, the Eye Ear Nose Throat Hospital, Fudan University, Shanghai, 200031, China. drlicai@hotmail.com
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Carcinoma, Neuroendocrine;
diagnosis;
surgery;
Female;
Humans;
Laryngeal Neoplasms;
diagnosis;
surgery;
Male;
Middle Aged;
Retrospective Studies
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2009;23(21):970-972
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the clinical characteristics and therapy of laryngeal neuroendocrine carcinoma (LNEC).
METHOD:Ten cases of LNEC treated in our department were retrospectively analyzed.
RESULT:Eight out of 10 cases were were atypical carcinoid: 1 case treated as supraglottic horizontal partial laryngectomy died 22 months after operation; 1 case was lost; the other 6 cases were followed up for more than 2 years. Two cases were small cell type, one received supra-cricoid partial laryngectomy-cricohyoidopexy (SCPL-CHP), neck dissection, and radiotherapy, but died after 14 months; the other was receiving radiotherapy.
CONCLUSION:LNEC is a rare malignant tumor and the diagnosis relies on clinical characteristics, histopathological and immunohistochemistry examination. The different types of LNEC should give different treatment protocols.
