The relationship between different types of lymph node metastasis and contralateral neck metastasis and their impact on prognosis.
- Author:
Chao GUAN
1
;
Xing GUO
;
Zimin PAN
;
Xuejun JIANG
Author Information
1. Department of Otolaryngology, the First Affiliated Hospital of China Medical University, Shenyang, 110001, China. guanchao999@hotmail.com
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Carcinoma, Squamous Cell;
diagnosis;
pathology;
Female;
Humans;
Laryngeal Neoplasms;
diagnosis;
pathology;
Lymph Nodes;
pathology;
Lymphatic Metastasis;
pathology;
Male;
Middle Aged;
Neck;
Neoplasm Staging;
Prognosis;
Retrospective Studies
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2010;24(5):221-223
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the relationship between different types of lymph node metastasis and contralateral neck metastasis and their impacts on prognosis.
METHOD:Two hundred and forty-eight patients with supraglottic carcinomas and complete follow-up were analyzed retrospectively. Transparent lymph node detection and continuous sectioning methods were applied on postoperative neck specimens.
RESULT:Cervical lymph node metastases were found in 115 patients and the lymph node metastatic rate was 46.4%. There were three types of lymph node metastases, 39 cases with single type, 34 with multiple type, 42 with fusion type. Contralateral metastatic rates were 5.1%, 44.1% and 61.9% in single, multiple and fusion type respectively. Contralateral metastasis was also related with tumor extension across midline and clinical N stages. The 3- and 5-year survival rates were 79.5% and 74.4% in single type, 61.8% and 41.2% in multiple type, 61.9% and 35.7% in fusion type.
CONCLUSION:Bilateral neck dissections should be undertaken in multiple and fusion types of lymph node metastasis. The lymph node metastatic type should be an important criteria to judge prognosis.
