Expression of SleX in nasal epithelium with chronic rhinosinusitis.
- Author:
Xuewei ZHU
1
;
Dongdong ZHU
;
Kewei SUN
;
Yusheng WANG
;
Zhen DONG
Author Information
1. Department of Otolaryngology Head and Neck Surgery, China-Japan Union Hospital, Jilin University, Changchun, 130033, China.
- Publication Type:Journal Article
- MeSH:
Adult;
Chronic Disease;
Female;
Humans;
Male;
Middle Aged;
Nasal Mucosa;
metabolism;
Neutrophils;
metabolism;
Oligosaccharides;
analysis;
Sinusitis;
metabolism;
Young Adult
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2008;22(20):917-919
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the expression of SleX in nasal epithelium in patients with chronic rhinosinusitis.
METHOD:Nine nasal epitheliums from patients with chronic rhinosinusitis and 7 normal controls were stained with SleX antibody by immunohistochemistry, and its expression were analyzed.
RESULT:Both nasal epithelial cells and neutrophils expressed SleX. Nearly 88.9% nasal epithelium from patients with chronic rhinosinusitis expressed SleX while 14.3% in normal control. Expression of SleX in nasal epitheliums from patients with chronic rhinosinusitis were higher than that in normal control. There were significant difference between two groups.
CONCLUSION:Nasal epithelium from patients with CRS is highly expressed SleX. It may involve the occurrence of chronic rhinosinusitis.
