Clinical study on aggressive rhinocerebral mucormycosis.
- Author:
Xuan WU
1
;
Geng XU
;
Weiping WEN
;
Jiebo GUO
Author Information
1. Hospital of Otolaryngology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China. entxgfess@163.com
- Publication Type:Case Reports
- MeSH:
Adult;
Brain Diseases;
diagnosis;
microbiology;
therapy;
Female;
Humans;
Male;
Middle Aged;
Mucormycosis;
diagnosis;
therapy;
Nose Diseases;
diagnosis;
microbiology;
therapy
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2008;22(23):1060-1067
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the clinical diagnosis, course and combined therapy of aggressive rhinocerebral mucormycosis.
METHOD:The clinical feature, diagnosis and therapy were analyzed in 5 cases with rhinocerebral mucormycosis throughout disease progress. Good treatments were found by analyzing curative effect of different treatment.
RESULT:One patient died within three weeks in hospital three patients survived from 2 months to 2 years; and one patient was alive over 3 years. The mortality rate was 80% in this study.
CONCLUSION:Rhinocerebral mucormycosis is always secondary to patients with severe diseases and bad immunologic function. The lesion can invade the orbit and brain quickly, and the mortality rate is high. The cause of the disease can be retarded by clearing up the focus early and removing the environment of fungi thriving with combined therapy. It is effective of remodelling the necrotic tissues by nasal endoscopy.
