A case of myocardial involvement in patient with MELAS syndrome.
- Author:
Won Ho KIM
1
;
Seung Chul LEE
;
Geu Ru HONG
;
Se Joong RIM
;
Namsik CHUNG
;
Ji Hoe HU
;
Sang Ho CHO
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. sejoong@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
MELAS syndrome;
Cardiomyopathy
- MeSH:
Acidosis, Lactic;
Adult;
Biopsy;
Brain;
Cardiomyopathies;
Cardiomyopathy, Hypertrophic;
Dyspnea;
Echocardiography;
Edema;
Female;
Hearing;
Humans;
MELAS Syndrome*;
Mitochondrial Myopathies;
Myocardium;
Parietal Lobe;
Stroke;
Thalamus
- From:Korean Journal of Medicine
2004;67(Suppl 3):S727-S731
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
MELAS syndrome is characterized by mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes, and cardiac involvement also frequently occurs. A 42-year-old female was admitted because of stroke like episodes and dyspnea. She had short status and hearing difficulty, and she complainded of general weakness. Brain MR revealed cortical sweeling and edema in temporal, parietal lobe and thalamus, which was not compatibe with stroke. Echocardiography revelaed hypertrophic left ventricular myocardium, resembling hypertrophic cardiomyopathy. Endomyocardial Biopsy confirmed myocardial involvement with MELAS syndrome.
