Two cases of isolated pulmonary valve infective endocarditis complicating ventricular septal defect.
- Author:
Mee Ah KIM
1
;
Han Cheol LEE
;
Sang Sun PARK
;
Seung Mook JUNG
;
Dal Soo LIM
;
Suk Keun HONG
;
Man Jong BAEK
Author Information
1. Division of Cardiology, Department of Internal Medicine, Sejong General Hospital, Puchun, Korea. glaraone@hanmail.net
- Publication Type:Case Report
- Keywords:
Infective endocarditis;
Pulmonary valve;
Ventricular septal defect
- MeSH:
Adult;
Alcoholism;
Catheter-Related Infections;
Causality;
Drug Users;
Dyspnea;
Echocardiography, Transesophageal;
Endocarditis*;
Female;
Fever;
Gentamicins;
Heart Diseases;
Heart Septal Defects, Ventricular*;
Heart Ventricles;
Humans;
Male;
Penicillins;
Pulmonary Valve*;
Sepsis;
Substance Abuse, Intravenous
- From:Korean Journal of Medicine
2004;67(Suppl 3):S740-S745
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Isolated infective endocarditis in the native pulmonary valve is an unusual clinical entity in non-intravenous drug users. Intravenous drug abuse, alcoholism, sepsis, catheter related infections and congenital heart diseases account for the majority of predisposing factors. We report two cases of isolated pulmonary valve infective endocarditis complicating ventricular septal defect (VSD). A 43 year-old male was admitted because of mild fever, pansystolic murmur on the left lower sternal border. Transthoracic and transesophageal echocardiography revealed a large perimembranous ventricular septal defect and vegetations at the pulmonary valve. After the intravenous use of penicillin and gentamicin, patch closure of VSD with resection of vegetations, resection of anomalous muscle bundles on the right ventricle outlet tract and pulmonary valvuloplasty was performed. A 43 year-old female was admitted with spiking fever, dyspnea. Transthoracic and transesophageal echocardiography showed a small perimenbranous ventricular septal defect with pulmonary valve vegetations. Intravenous penicillin and gentamicin were continued for 4 weeks and she is doing well.
