A Case of T Cell Chronic Lymphocytic Leukemia Associated with Pure Red Cell Aplasia.
- Author:
Sang Seuk PARK
1
;
Hong LEE
;
Jae Ho JANG
;
Hyun Mo SONG
;
Seung Jung LEE
;
Jae Yong KWAK
;
Chang Yeol YIM
;
Byung Moon CHOI
;
Yong Gon CHO
;
Mi Kyung LEE
;
Yeun Jeong KIM
;
Hae Su LEE
;
Sam Im CHOI
Author Information
1. Department of Internal Medicine, College of Medicine, Chonbuk University Hospital, Chonju, Korea.
- Publication Type:Case Report
- Keywords:
Pure red cell aplasia;
Chronic lymphocytic leukemia;
T lymphocyte
- MeSH:
Acquired Immunodeficiency Syndrome;
Aged;
Anemia;
Bone Marrow;
Common Variable Immunodeficiency;
Humans;
Leukemia, Lymphocytic, Chronic, B-Cell*;
Leukemia, Lymphoid;
Lupus Erythematosus, Systemic;
Lymphocytosis;
Red-Cell Aplasia, Pure*;
Reticulocytes;
Thymoma
- From:Korean Journal of Medicine
1997;52(2):253-256
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pure red cell aplasia(PRCA) is characterized by anemia, absence of reticulocytes in the peripherial blood and selective erythroid hypoplasia in the bone marrow. Acquired PRCA is often associated with thymoma but may also occur in many diverse conditions, such as chromic lymphocytic leukemia, systemic lupus erythematosus, autoimmune disorders, T gamma lymphocytosis, acquired hypogammaglobulinemia, acquired immunodeficiency syndrome. Recently we experienced a case of T cell chronic lymphocytic leukemia associated with pure red cell aplasia. A 65-year-old man was presented with severe anemia. absolute reticulocytopenia, hepatosplenomegaly and lymphocytosis(T cell marker' CD2, CD7 positive). Bone marrow findings showed a marked decrease in erythroid precursors and normal maturations of granulocytic and megakaryocytic series, which were consistent with pure red cell aplasia. So we report this case with a review of the literature.
