Progress in serum markers for non-alcoholic fatty liver disease
10.3760/cma.j.issn.1009-9158.2019.03.004
- VernacularTitle:非酒精性脂肪性肝病血清学检测进展
- Author:
Xiaoxiao WANG
1
;
Xiaohe LI
;
Feng LIU
;
Lai WEI
Author Information
1. 北京大学人民医院北京大学肝病研究所丙型肝炎和肝病免疫治疗北京市重点实验室 100044
- Keywords:
Non-alcoholic fatty liver disease;
Serologic tests;
Clinical laboratory techniques
- From:
Chinese Journal of Laboratory Medicine
2019;42(3):165-169
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing gradually. The pathological changes of NAFLD can progress from simple hepatic steatosis to steatohepatitis , and to advanced liver fibrosis ultimately. Accurate diagnosis and identification of nonalcoholic steatohepatitis (NASH) and fibrosis patients are necessary for the treatment and management of NAFLD. The traditional gold standard--liver biopsy is an invasive procedure that is not suitable for clinical practice and clinical trials. Some non-invasive markers for NAFLD based on serological testing will be a new direction for the diagnosis of NAFLD. This article reviews the laboratory tests, clinical parameters, genomic and metabolomics-related NAFLD non-invasive serological markers.
