Mesenchymal stem cells derived exosomes:an alternative drug carrier for eye disease
10.3760/cma.j.issn.1005-1015.2019.02.021
- VernacularTitle:间充质干细胞外泌体:眼部给药的可选择载体
- Author:
Ruotian XIE
1
;
Xiaomin ZHANG
Author Information
1. 天津医科大学眼科医院天津医科大学眼科研究所天津医科大学眼视光学院 300384
- Keywords:
Mesenchymal stem cells;
Exosomes;
Drug carriers;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2019;35(2):211-214
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells (MSCs) are considered as an ideal treatment for multiple diseases including ocular disease.Recent studies have demonstrated that MSCs-derived exosomes have similar functions with MSCs.Exosomes are nanovesicles surrounded by a phospholipid layer that shuttle active cargo between different cells.They are capable of passing the biological barrier and have potentials to be utilized as natural carrier for the ocular drug delivery.