Risk factors of venous thromboembolism following lung cancer resection
10.3760/cma.j.issn.1001-4497.2019.03.002
- VernacularTitle:肺癌手术患者出院后静脉血栓栓塞危险因素分析
- Author:
Yulong XUAN
1
;
Bin CAO
;
Baojun CHEN
;
Tao WANG
;
Minke SHI
;
Yong ZHOU
Author Information
1. 南京大学医学院附属南京鼓楼医院心胸外科 210008
- Keywords:
Lung cancer surgery;
Venous thromboembolism;
Risk factors;
Prophylaxis
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2019;35(3):133-136
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify risk factors for postdischarge venous thromboembolism(VTE) following lung resection.Methods Patients undergoing anatomic resection for lung cancer were identified in our institution from 2005-2015.Patient demographic and clinical characteristics were evaluated for any association with post-discharge VTE.Predictors of post-discharge VTE were identified using multivariable analysis.Results VTE occurred in 1.6％ (117) of the 7 154 patients identified.43.6％ (51) VTE events occurred following hospital discharge.Undergoing pneumonectomy was associated with a threefold increased risk for post-discharge VTE compared with lobectomy(2.03％ vs.0.64％,P ＜ 0.01),as was open resection compared to minimally invasive resection(0.86％ vs.0.53％,P＜0.01).Prolonged operative time(＞75％) was also associated with increased risk for post-discharge VTE compared to shorter operative time.Multivariable analysis identified older age,obesity,pneumonectomy,and prolonged operative time as independent predictors for post-discharge VTE.Conclusion The risk for VTE extends after hospital discharge,few patients are managed with post-discharge prophylaxis.Post-discharge prophylaxis should be considered for those at high risk for VTE,particularly for older patients,those who are obese,and following extended or lengthy resections.
