Paraneoplastic limbic encephalitis with double positive anti-Hu and Yo antibodies: a case report
10.3760/cma.j.issn.1006-7876.2019.05.008
- VernacularTitle:抗Hu、Yo抗体双重阳性副肿瘤性边缘叶脑炎一例
- Author:
Yanlei GENG
1
;
Jinbo CHEN
;
He MA
;
Hongliang CHEN
;
Xiaowen SONG
;
Hong LI
;
Shujun LU
;
Yipeng SU
;
Yaozhi HU
;
Cong LI
;
Xuechuan GENG
Author Information
1. 滨州医学院附属医院神经内科
- Keywords:
Paraneoplastic syndromes,nervous system;
Limbic encephalitis;
Autoantibodies
- From:
Chinese Journal of Neurology
2019;52(5):406-409
- CountryChina
- Language:Chinese
-
Abstract:
Paraneoplastic neurological syndromes (PNS) are a rare group of immune-mediated disorders that affect the central and peripheral neuromuscular system in association with cancer.If the limbal lobe system of the brain is involved,it will show paraneoplastic limbal encephalitis(PLE).The discern of patients with PNS is challenging since tumors causing paraneoplastic neurologic disorders are often asymptomatic and sometimes occult.We report a case of PLE with double positive anti-Hu and Yo antibodies,and further analyze and discuss it in conmbination with relevant literature to improve the understanding of the disease.