Deep brain stimulation for drug-resistant epilepsy
10.3760/cma.j.issn.1006-7876.2019.04.015
- VernacularTitle:深部脑刺激治疗耐药癫痫研究进展
- Author:
Yanting SHI
1
;
Qianwen DU
;
Kejun ZANG
;
Huaikuan WU
;
Yongxin SU
;
Xuewu LIU
Author Information
1. 山东大学齐鲁医院神经内科
- Keywords:
Stimulation;
Intractable epilepsy Efficacy;
Predictor;
Safety
- From:
Chinese Journal of Neurology
2019;52(4):339-343
- CountryChina
- Language:Chinese
-
Abstract:
Deep brain disease stimulation (DBS) is commonly used to treat movement disorders such as Parkinson disease,and current evidence suggests that DBS may also be useful for refractory epilepsy and is affected by a variety of factors.Studies show that stimulation of the anterior nucleus of the thalamus and hippocampus may decrease the frequency of refractory seizures.The efficacy of stimulating other targets remains inconclusive.An absence of structural abnormality on imaging and electrode position are associated with stimulation efficacy.Certain seizure types may respond more favorably to specific targets.There are several factors that potentially predict seizure outcome following DBS,but more large-scale clinical trials are needed.
