Research progress in hemorrhagic transformation after intravenous thrombolysis
10.3760/cma.j.issn.1006-7876.2019.04.014
- VernacularTitle:静脉溶栓后出血性转化研究进展
- Author:
Wenying XU
1
;
Li TIAN
;
Jinwei LI
;
Weishuang XUE
;
Weiyu TENG
Author Information
1. 中国医科大学附属第一医院神经内科
- Keywords:
Stroke;
Tissue plasminogen activator;
Intravenous thrombolysis;
Hemorrhagic transformation
- From:
Chinese Journal of Neurology
2019;52(4):334-339
- CountryChina
- Language:Chinese
-
Abstract:
Stroke has increasingly become one of the three major diseases threatening human beings,among which acute ischemic stroke is the most common.Intravenous thrombolysis has become the first choice for acute ischemic stroke,but a large number of studies have shown that intravenous thrombolysis increases the risk of hemorrhagic transformation.The latest advances in clinical types,incidence,mechanism and risk factors of hemorrhagic transformation after thrombolysis with recombinant human tissue plasminogen activator are reviewed in this article,and the possible predictors of hemorrhagic transformation are discussed,aiming to provide new reference for clinical thrombolytic therapy.