Pulmonary Nodular Lymphoid Hyperplasia Associated with Sjögren's Syndrome.
10.3904/kjim.2007.22.3.192
- Author:
Moo Kon SONG
1
;
Young Mi SEOL
;
Young Eun PARK
;
Yun Seong KIM
;
Min Ki LEE
;
Chang Hun LEE
;
Yeon Ju JEONG
Author Information
1. Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea. yskimdr@yahoo.co.kr
- Publication Type:Journal Article
- Keywords:
Pseudolymphoma;
Pulmonary nodular hyperplasia;
Sj?gren's syndrome
- MeSH:
Biopsy;
Female;
Humans;
Immunohistochemistry;
Middle Aged;
Pseudolymphoma/complications/*pathology/*radiography;
Sjogren's Syndrome/*complications;
Thoracic Surgery, Video-Assisted;
Tomography, X-Ray Computed
- From:The Korean Journal of Internal Medicine
2007;22(3):192-196
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pulmonary nodular lymphoid hyperplasia (NLH) is a term first suggested by Kradin and Mark to describe one or more pulmonary nodules or localized lung infiltrates consisting of reactive lymphoid proliferation. To date, there have been only a few cases of pulmonary NLH reported associated with autoimmune disorders. There is no case of NLH associated with Sj?gren's syndrome from Korea in the medical literature. A 56-year-old woman was referred to our hospital with cough productive of sputum and chest tightness. The Computed tomography scans of the chest revealed multiple and well-defined peribronchiolar nodular opacities. A video assisted thoracoscopic surgery (VATS) biopsy was performed and the nodular opacity in the lung parenchyma was pathologically confirmed as NLH. Through meticulous review of patient's record, we found that she had been suffering from dry eye and dry mouth. The symptoms suggested Sj?gren's syndrome, which was confirmed by specific laboratory tests including the Schirmer test, anti-nuclear antibody and anti-Ro/La antibody. The patient is followed regularly and has no further progression of symptoms.
