MicroRNAs and lncRNAs in psoriasis
10.3760/cma.j.issn.0412-4030.2019.05.016
- VernacularTitle:microRNA和lncRNA在银屑病中的研究进展
- Author:
Yu HU
1
;
Min CHEN
;
Heng GU
Author Information
1. 中国医学科学院北京协和医学院皮肤病医院理疗科
- Keywords:
Psoriasis;
MicroRNAs;
LncRNAs
- From:Chinese Journal of Dermatology
2019;52(5):350-353
- CountryChina
- Language:Chinese
-
Abstract:
Psoriasis is a common chronic inflammatory skin disease,and commonly considered as a T cell-mediated abnormal immune disease with genetic predisposition at present.Recent studies have indicated that microRNAs and lncRNAs play important roles in occurrence and development of a variety of inflammatory immune diseases.It has been confirmed that microRNAs and lncRNAs participate in the occurrence of psoriasis by regulating the proliferation and differentiation of keratinocytes,release of inflammatory factors,and angiopoiesis.This review summarizes research advances in roles of microRNAs and lncRNAs in psoriasis.
