Advances in preimplantation genetic diagnosis
10.3760/cma.j.issn.1000-6699.2019.03.002
- VernacularTitle:胚胎植入前遗传学诊断研究进展
- Author:
Xueli LIU
1
;
Hefeng HUANG
;
Chenming XU
Author Information
1. 上海交通大学医学院附属国际和平妇幼保健院
- Keywords:
Preimplantation genetic diagnosis;
Microarray technology;
Next-generation sequencing
- From:
Chinese Journal of Endocrinology and Metabolism
2019;35(3):185-189
- CountryChina
- Language:Chinese
-
Abstract:
In the past 20 years,molecular genetic technology has developed rapidly.The leap forward development of single-cell genetic diagnosis technologies represented by whole genome amplification combined with microarray technology or next-generation sequencing not only increased the accuracy of preimplantation genetic diagnosis (PGD) but also greatly expanded the variety and scope of detectable diseases.This paper systematically reviews the clinical application of PGD as well as recent progress of related technologies.
