Treatment-Resistant Depression Entering Remission Following a Seizure during the Course of Repetitive Transcranial Magnetic Stimulation.

Author: Ju Wan KIM ¹ ; Kyung Yeol BAE ; Sung Wan KIM ; Hee Ju KANG ; Il Seon SHIN ; Jin Sang YOON ; Jae Min KIM
Author Information

1. Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea. jmkim@chonnam.ac.kr
Publication Type:Case Report
Keywords: Treatment resistant depression; Transcranial magnetic stimulation; Adverse event; Seizure; Remission
MeSH: Depression*; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Headache; Humans; Seizures*; Syncope; Transcranial Magnetic Stimulation*
From:Psychiatry Investigation 2016;13(4):468-471
CountryRepublic of Korea
Language:English
Abstract: Major depressive disorder is often resistant to antidepressant treatment. Repetitive transcranial magnetic stimulation (rTMS) has been used in treatment-resistant depression (TRD). Known adverse events of rTMS include transient headache, local pain, syncope, seizure induction, and hypomania induction. This report outlines a patient with TRD who unexpectedly improved following a seizure during the course of rTMS, which has never been reported.