Efficacy of nalbuphine in preventing shivering after neuraxial anesthesia in patients undergoing cesarean section
10.3760/cma.j.issn.0254-1416.2018.12.007
- VernacularTitle:纳布啡预防剖宫产术患者椎管内麻醉后寒战的效果
- Author:
Shaohua ZHENG
1
;
Pingyi SONG
;
Zheng GUAN
;
Bin GUAN
;
Yang BI
;
Xiaopeng MEI
Author Information
1. 710061,西安交通大学第一附属医院麻醉科
- Keywords:
Nalbuphine;
Shivering;
Cesarean section;
Anesthesia,conduction
- From:
Chinese Journal of Anesthesiology
2018;38(12):1434-1436
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of nalbuphine in preventing shivering after neuraxial anesthesia in patients undergoing cesarean section.Methods Eighty American Society of Anesthesiologists physical status Ⅰ or Ⅱ patients,aged 20-35 yr,weighing 55-80 kg,undergoing elective cesarean section under neuraxial anesthesia,were divided into nalbuphine group (group N,n=40) and control group (group C,n=40) using a random number table method.After delivery,nalbuphine 0.1 mg/kg was intravenously injected immediately before clamping the umbilical cord in group N,and the equal volume of normal saline was given instead in group C.Ramsay sedation score was recorded before giving nalbuphine,at 5 min after giving nalbuphine,and at the end of surgery.The development of shivering was recorded from the end of nalbuphine administration until the end of surgery,and the shivering intensity was estimated using Wrench grading.The development of over-sedation,nausea and vomiting,bradycardia,hypotension and dizziness was recorded from the end of nalbuphine administration until the end of surgery.Results Compared with group C,Ramsay sedation scores were significantly increased at 5 min after giving nalbuphine and at the end of surgery,the incidence of shivering was decreased,the shivering intensity was reduced (P＜0.05),and no significant change was found in the incidence of adverse reactions in group N (P＞ 0.05).Conclusion Nalbuphine can prevent the occurrence of shivering after neuraxial anesthesia in patients undergoing cesarean section.
