Accuracy of variation of end-tidal pressure of carbon dioxide in predicting fluid responsiveness in patients undergoing resection of gastrointestinal tumor
10.3760/cma.j.issn.0254-1416.2018.11.019
- VernacularTitle:PETCO2变异度预测胃肠肿瘤手术患者容量反应性的准确性
- Author:
Cheng CHEN
1
;
Ju GAO
;
Ke LUO
;
Luojing ZHOU
;
Mengyuan CHEN
;
Tianfeng HUANG
;
Yali GE
Author Information
1. 中南大学湘雅二医院麻醉科
- Keywords:
Carbon dioxide;
Partial pressure;
Vascular capacitance
- From:
Chinese Journal of Anesthesiology
2018;38(11):1351-1353
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy of variation of the end-tidal pressure of carbon dioxide (△PETCO2) in predicting the fluid responsiveness in patients undergoing resection of gastrointestinal tumor.Methods Forty-six patients of both sexes,aged 40-64 yr,with body mass index of 20-24 kg/m2,of American Society of Anesthesiologists physical status Ⅱ or Ⅲ,undergoing elective resection of gastrointestinal tumor with general anesthesia,were enrolled in the study.When the change in mean arterial pressure was less than 10％ within 5 min after anesthesia induction,250 ml Ringer's solution was rapidly infused over 10 min via the peripheral vein.Increase in cardiac index after volume expansion ≥ 15％ was considered to be a positive response.The receiver operating characteristic curve for △PETCO2 in determining fluid responsiveness was drawn.Results The results of receiver operating characteristic curve analysis showed that the area under the curve for △PETCO2 in determining fluid responsiveness (95％ confidence interval) was 0.826 (0.730-0.942,P＜0.05),the critical value 21.9％,sensitivity 76.5％,specificity 90.9％.Conclusion △PETCO2 can accurately predict the fluid responsiveness in patients undergoing resection of gastrointestinal tumor.
