A review on evaluating application of abnormal iron deposition in brain on diagnosis and differential diagnosis of Parkinson's disease
10.3760/cma.j.issn.0254-9026.2019.05.029
- VernacularTitle:铁沉积测定在帕金森病诊断及鉴别诊断中的应用
- Author:
Wei XIONG
1
;
Beisha TANG
;
Lifang LEI
Author Information
1. 中南大学湘雅三医院神经内科
- Keywords:
Iron;
Parkinson disease;
Diagnosis
- From:
Chinese Journal of Geriatrics
2019;38(5):594-600
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson's disease (PD)is a common neurological degenerative diseases,and its diagnosis mainly depends on a patient's clinical manifestations and the response to dopaminergic drugs.The coincidence rate between clinical diagnosis and pathological diagnosis for PD is only 70%-80%.It is found that abnormality of intracranial iron deposition is one of the important pathological changes in PD progression.Therefore,it can be helpful to detect the abnormal iron deposition in brain using MRI and Doppler sonography for early diagnosis and differential diagnosis of PD.