Evaluation of pulmonary artery blood flow and right heart function using phase-contrast magnetic resonance imaging in elderly patients with chronic obstructive pulmonary disease
10.3760/cma.j.issn.0254-9026.2019.05.017
- VernacularTitle:磁共振相位对比法评价老年慢性阻塞性肺疾病患者肺动脉血流及右心功能
- Author:
Chen ZHANG
1
;
Hui CHEN
;
Lei ZHAO
;
Yao XIAO
;
Guangfa ZHU
;
Zhanming FAN
;
Xiaohai MA
Author Information
1. 首都医科大学附属北京安贞医院医学影像科 100029
- Keywords:
Magnetic resonance imaging;
Pulmonary disease,chronic obstructive;
Pulmonary artery;
Ventricular function
- From:
Chinese Journal of Geriatrics
2019;38(5):542-546
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of phase-contrast magnetic resonance imaging (PC-MRI)in evaluating pulmonary artery blood flow and right ventricular(RV)function in elderly patients with chronic obstructive pulmonary disease (COPD).Methods Twenty-four elderly patients with COPD admitted to Beijing Anzhen Hospital between February 2016 and June 2017 were enrolled in this retrospective study.Based on pulmonary artery pressure evaluated by right heart catheterization,COPD patients were divided into a pulmonary hypertension group (PH group,n =12)and a non-PH group(n=12).Pulmonary artery blood flow velocity and volume,pulmonary arterial compliance and right heart function parameters including ejection fraction,end diastolic volume,endsystolic volume and cardiac output,and 6-min walking distance evaluated by PC-MRI were compared between the two groups.Results There were significant differences in peak flow velocity[(88.1 ±16.0)cm/s vs.(59.8± 13.8) cm/s,P =0.005],flow volume [(80.7± 22.0) ml/s vs.(53.2± 26.7)ml/s,P=0.012],main pulmonary artery compliance[(42.3± 14.6)vs.(22.7± 10.8),P =0.001],right ventricular ejection fraction [(48.4 ± 13.4) ％ vs.(37.6 ± 11.1) ％,P =0.000],end-diastolic volume[(64.6±22.5)ml vs.(72.5±22.8)ml,P =0.030]and end-systolic volume[(50.6±33.1)ml vs.(41.7±33.1)ml,P =0.040]between the non-PH and PH groups,while there was no significant difference in cardiac output between the non-PH and PH groups[(34.2±10.8)ml vs.(34.4±8.3)ml,P =0.080].Pearson's correlation analysis showed that 6-minute walking distance had good correlations with right ventricular ejection fraction(r =0.49),forced expiratory volume in 1 s(FEV1)(r=0.60)and main pulmonary artery diameter(r=0.61).Conclusions PC-MRI is a noninvasive imaging method for quantitative analysis of pulmonary artery dynamics and right heart function for the elderly with COPD,and it can provide information for evaluating therapeutic effects and prognosis.
