Diagnostic value of combined serum CA19-9 with CT scanning in patients with pancreatic cancer
10.3760/cma.j.issn.0254-9026.2019.04.016
- VernacularTitle:血清CA19-9联合CT检查胰腺癌的临床价值分析
- Author:
Yong WANG
1
;
Li YANG
;
Jiao HAN
Author Information
1. 郑州人民医院消化内科
- Keywords:
Pancreatic neoplasms;
Antigens,neoplasm
- From:
Chinese Journal of Geriatrics
2019;38(4):416-418
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of combined serum tumor marker CA19-9 with CT scanning in the patients with pancreatic cancer.Methods A total of 89 patients with suspected pancreatic cancer diagnosed by CT scanning were selected at our hospital from May 2012 to December 2016.The detected results of serum CA19-9 were recorded,and the specificity,sensitivity,positive and negative predictive value of serum CA19-9 in the diagnosis of pancreatic cancer were statistically calculated and analyzed.The correlations between the pre-and post-operative serum levels of CA19-9 and the survival time in pancreatic cancer patients undergoing operation were analyzed.Results The specificity,sensitivity,positive predictive value and negative predictive value of serum CA19-9 combined with CT scanning in the diagnosis of pancreatic cancer were 97.2％,86.4％,100.0 ％,94.0 ％ respectively.With the increase of preoperative serum levels of CA19-9,the resection rate and median postoperative survival time gradually decreased.Patients with normal serum levels of CA19-9 after operation had longer postoperative survival time than patients with high postoperative serum levels of CA19-9.Conclusions As one of the tumor markers of pancreatic cancer,serum CA19-9 detection has a high diagnostic sensitivity.Combined with CT scanning,serum CA19-9 detection can significantly improve the diagnostic accuracy of pancreatic cancer.Serum CA19-9 can also be used as a mean of efficacy evaluation after radical resection of pancreatic cancer.
