Relationship between onset of myocardial infarction to bivalent antibiotics therapy and outcome in elderly female myocardial infarction patients
10.3969/j.issn.1009-0126.2019.05.004
- VernacularTitle:老年女性心肌梗死患者发病至给予双联抗血小板治疗时间与预后的相关性研究
- Author:
Rongpin DU
1
;
Lili WANG
;
Yanjun LIU
;
Ruyi LI
;
Yanru LI
;
Qi HUA
Author Information
1. 河北省人民医院心内科
- Keywords:
myocardial infarction;
coronary occlusion;
platelet aggregation inhibitors;
myocardial reperfusion;
prognosis
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2019;21(5):462-464
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the relationship between onset of myocardial infarction(MI)to bivalent antibiotics therapy and outcome in elderly female MI patients.Methods One hundred and fourteen elderly MI patients admitted to our hospital from January 2016to January 2018were divided intoΔT≤188min group(n=57)andΔT>188min group(n=57)according to the onset of MI to bivalent antibiotics therapy.The major adverse cardiac events(MACE),arrhythmia,angina pectoris,heart failure and death were compared between the two groups.Results MACE occurred in 44out of the 144MI patients included in this study.Of the 44MI patients,17died,6 were diagnosed with arrhythmia,16were diagnosed with angina pectoris,5were diagnosed with heart failure.The incidence of arrhythmia,heart failure and the mortality were significantly higher while the incidence of angina pectoris was significantly lower inΔT≤188min group than inΔT> 188min group(7.0%vs 3.5%,7.0%vs 1.8%,15.8%vs 14.0%,7.0%vs 21.1%,P<0.05).Age,diabetes,ΔT,hyperlipidemia,hypertension and coronary artery disease were the independent influencing factors for the poor outcome in MI patients(P<0.05,P<0.01).Conclusion TheΔT should be shortened,the MI patients should be timely treated,the criminal blood vessels should be opened,and the ischemic myocardium should be saved in order to prevent the occurrence of severe cardiovascular events and reduce the mortality in elderly MI patients.