Clinical application of anti-Müllerian hormone and its detection method

VernacularTitle:抗米勒管激素检测及其应用进展
Author: Chenhui LEI ¹ ; Yizhen SHI
Author Information

1. 苏州大学附属第二医院核医学科 215004
Keywords: Anti-Mullerian hormone; Ovarian function tests; Enzyme-linked immunosorbent assay; Chemiluminescent measurements; Trends
From: Chinese Journal of Nuclear Medicine and Molecular Imaging 2019;39(5):308-311
CountryChina
Language:Chinese
Abstract: Anti-Müllerian hormone (AMH),a dimer glycoprotein secreted by sustentacular cells of testis and ovarian granulosa cells,belonging to the transforming growth factor β super-family.AMH is able to regulate follicular development and participate in follicular growth process,and it is relatively constant throughout the menstrual cycle compared with other ovarian reserve indicators.At present,AMH is widely used to evaluate ovarian reserve and to diagnose and evaluate the development and prognosis of ovarian diseases.It has been increasingly applied in the field of female assisted reproduction in recent years.With the development of detection technology,the sensitivity and accuracy of methods for detecting AMH are gradually improved.This review summarizes the research background,mechanism of action,clinical applications and detecting methods of AMH.