24-hour Ambulatory Blood Pressure in Normal Tension Glaucoma: Associations with Retinal Vessel Diameter and Visual Field Defect Progression.
10.3341/jkos.2017.58.11.1242
- Author:
Aerin JO
1
;
Hyungwoo LEE
;
Byung Joo CHO
Author Information
1. Department of Ophthalmology, Konkuk University School of Medicine, Seoul, Korea. bjcho@kuh.ac.kr
- Publication Type:Original Article
- Keywords:
Nocturnal dip;
Normal tension glaucoma;
Retinal vessel;
Vessel narrowing;
24-hour ambulatory blood pressure monitoring
- MeSH:
Blood Pressure*;
Glaucoma;
Hemodynamics;
Humans;
Low Tension Glaucoma*;
Photography;
Retinal Vessels*;
Retinaldehyde*;
Visual Fields*
- From:Journal of the Korean Ophthalmological Society
2017;58(11):1242-1247
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the correlation between 24-hour ambulatory blood pressure (BP) monitoring and peripapillary retinal vessel width and visual field (VF) defect progression in normal tension glaucoma (NTG) patients. METHODS: All patients were classified by 24-hour ambulatory BP monitoring as non-dipper (nocturnal dip < 10%) and dipper (nocturnal dip ≥ 10%) group. Vessel diameter, mean deviation (MD) value by VF test and VF progression from Glaucoma Progression Analysis (GPA) were compared among non-dipper and dipper groups. RESULTS: Retinal arterial diameter was wider in the non-dipper group compared to the dipper group (p = 0.015), while retinal venous diameter had no significant relationship between the two groups (p = 0.131). The MD value at baseline and 2 years after was worse in the non-dipper group than the dipper group, respectively (p = 0.006, p = 0.030). But, there was no significant relationship between nocturnal dip and GPA progression (p = 0.658). CONCLUSIONS: There was a statistically significant correlation between nocturnal dips and retinal arterial diameter and MD values. These results suggest that non-invasive fundus photography can predict hemodynamic features like nocturnal dip.
