Feasibility study of in vivo fingernail dosimetry by electron paramagnetic resonance
10.3760/cma.j.issn.0254-5098.2019.05.013
- VernacularTitle:电子顺磁共振在体测量指甲剂量方法的可行性研究
- Author:
Ye TIAN
1
;
Junwang GUO
;
Jierui ZOU
;
Lei MA
;
Guofu DONG
;
Jianbo CONG
;
Ke WU
Author Information
1. 军事科学院军事医学研究院辐射医学研究所核应急技术与保健物理学研究室北京市放射生物学重点实验室(No.BZ0325) 100850
- Keywords:
Electron paramagnetic resonance;
Fingernail;
In vivo;
Accident;
Dosimetry
- From:
Chinese Journal of Radiological Medicine and Protection
2019;39(5):392-396
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility of EPR in vivo fingernail dosimetry to address the difficulty in separating mechanically induced signals from fingernail EPR dosimetry for need of nuclear medical emergency aid.Methods Using the specially designed EPR in vivo measurement system,uncut fingernails were measured to obtain the characteristics of EPR signal without mechanically induced signals.The in vivo fingernail experiment was carried out to evaluate the impact of in vivo condition on the spectra.Actual in vivo measurement experiment was conducted to evaluate the interference of the in vivo condition on EPR spectra.Results The background signal distribution of uncut fingernails was obtained and background signals had no significant difference between male and female(P＞0.05).The dose response curve in the range of 2-10 Gy was established,and the half-life of the fingernail radiation-induced signal was approximately 5 d.The water treatment combined with temperature-changing was established for restoring the background signal.EPR signal obtained after restoring treatment has no significant difference with background signal (P＞ 0.05).The EPR spectra of in vivo fingernails were obtained.Conclusions The EPR spectra without mechanically induced signals can be acquired by this method.The feasibility of the in vivo fingernail EPR dosimetry is preliminarily verified.
