MRI diagnosis and clinical analysis for autosomal dominant polycystic kidney disease related male infertility
10.3760/cma.j.issn.1005-1201.2019.02.007
- VernacularTitle:常染色体显性多囊肾病相关精道梗阻所致男性不育的MRI特征
- Author:
Huanjun WANG
1
;
Yang PENG
;
Fan ZHANG
;
Haoqin ZHANG
;
Xuyang XIAO
;
Yan GUO
;
Jian GUAN
Author Information
1. 中山大学附属第一医院医学影像科
- Keywords:
Polycystic kidney disease;
Obstructive azoospermia;
Seminal vesicle cyst;
Ejaculatory duct cyst;
Magnetic resonance imaging
- From:
Chinese Journal of Radiology
2019;53(2):115-120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the recognition and knowledge of autosomal dominant polycystic kidney disease (ADPKD) related male infertility through investigation for MRI characteristics of this disease. Methods Fourteen patients confirmed with ADPKD related obstructive azoospermia were retrospectively analyzed. All patients referred to clinic with male infertility, and obstructive azoospermia were additionally confirmed by laboratory tests and clinical examination. Subsequent abdominopelvic MR examinations were performed to comfirm obstructive factors and obstructive location. All patients were performed an abdominopelvic MR examination including non-enhanced and enhanced MR. MR imaging characteristics were analyzed and summarized by two experienced radiologists. Results MRI results for all cases were classified into 4 groups:10 cases with bilateral polycystic kidneys and bilateral seminal vesicle cysts, 2 cases with bilateral polycystic kidneys, polycystic liver and bilateral seminal vesicle cysts, 1 case with bilateral polycystic kidneys, polycystic liver and absence of bilateral seminal vesicles, 1 case with bilateral cystic kidneys, bilateral seminal vesicle cysts as well as Müllerian duct cyst. A wide range of coronal T2WI scan was necessary to observe cystic lesions in both liver and bilateral kidneys as well as abnormal changes in pelvis. The obstructive sites in all cases were located in level from ejaculatory duct to seminal vesicle. Bilateral seminal vesicle cysts presented as significantly dilated glandular ducts of seminal vesicles, in which flocculence or nodular sediment can be found. Conclusion Male infertility caused by ADPKD-related deferential duct obstrution is characterized by bilateral polycystic kidney disease and Seminal vesicle ejaculatory duct obstruction in MRI, which can be combined with other abnormalities.
